D-mannose
D-mannose is a simple sugar with a structure very close to glucose. It is secreted in very small amounts by our body, and covers the urinary tract. Let’s discover this molecule recently used as a food supplement…
Mannose is a 6-carbon, aldohexose. the root of the word «manna» it comes from the «manna» harvested by the Hebrews during the exodus, which is the sweet secretion of certain trees (the sap) found in the deserts of the Middle East.
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D-mannose can be produced by the oxidation of mannitol, which is a natural sweetener with a sweetness 0.7 times greater than sugar. is also a sugar that passes quickly through the body without being absorbed.
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D-mannose is present in some fruits, particularly blueberries.
D-mannose is also found in significant amounts in the sap of some trees and shrubs and in corn, and in smaller quantities in peaches, oranges, pineapples, apples and blueberries.
Benefits and virtues
The main therapeutic action of D-Mannose is to fight against urinary tract infections, also called cystitis.
The Cystitis is a very common disease in women and girls. It is caused 90% of the time by an intestinal bacterium called E.coli, which contaminates the urethra.
This bacteria, when it reaches the bladder, creates an infection called cystitis. Cystitis is very painful and disabling, and in some women it is very recurrent or even chronic.
It can be dangerous for the kidneys and can even cause kidney failure if not treated properly.
The most common treatment for cystitis is antibiotic treatment, with all the side effects that this entails (digestive problems, vaginal infections, etc.).
It is also known today that it is not advisable to multiply antibiotic treatments at the risk of generating bacterial resistance.
This is where D-mannose comes in, a simple sugar that naturally coats the cells of the urinary tract and is found in certain fruits.
D-mannose absorbed as treatment, creates a molecular decoy for that the E.Coli adhere to it instead of adhering to the urethra and contaminating it. The D-Mannose/E.Coli couple is eventually shed in the urine, protecting the bladder from infection.
Dosage
A daily dose of 2 to 4 g of D-mannose capsule, powder or tablet is generally recommended, with 500 mg taken every 2 to 3 hours for at least 5 days.
Symptoms usually improve within 24 hours, but it is important to continue treatment for 2 to 3 days after symptoms have completely resolved.
If the symptoms persist with the same intensity beyond 3 days, consult your doctor to verify that the cystitis has no other cause than E.Coli.
D-Mannose can be taken as a treatment, but also as a prevention for cystitis, when you are feeling frail or debilitated, or after a long course of antibiotics, which can cause a UTI.
Side effects and contraindications
Since D-mannose is a natural sugar, it is harmless and does not cause adverse effects in any prescribed dose.
Since this sugar is not metabolized like other sugars, it is not contraindicated in diabetics or prediabetics.
Children and pregnant women can also start treatment with D-Mannose.
Let’s go further… new scientific discoveries…
In 2014, a clinical trial of D-mannose powder was studied on its preventive effect in women prone to cystitis and used to taking antibiotic treatments.
The researchers compared three groups of women: the first treated preventively with D-Mannose, the second treated only with antibiotics and the third without treatment.
The results showed that the women in the first group, treated with D-Mannose, had fewer recurrences than the other two groups of women.
These encouraging results therefore suggest the preventive effect of D-mannose on recurrent cystitis.
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